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Publications

Cardiovascular Biology Research Program

Dr. Lupu In The News

OMRF scientists discover promising new path for treating traumas

Florea Lupu, Ph.D. Associate Member / Sr. Lab Director, Cardiovascular Biology Research   Program Adjunct Associate Professor, Department of Pathology, University of Oklahoma   Health Sciences Center

Recent Publications
Fu J, Gerhardt H, McDaniel JM, Xia B, Liu X, Ivanciu L, Ny A, Hermans K, Silasi-Mansat R, McGee S, Nye E, Ju T, Ramirez MI, Carmeliet P, Cummings RD, Lupu F, Xia L. Endothelial cell O-glycan deficiency causes blood/lymphatic misconnections and consequent fatty liver disease in mice. J Clin Invest 118:3725-3737, 2008. [Abstract]

Lupu F. "Crossroads in Sepsis Research" Review Series Overview of the pathophysiology of sepsis. J Cell Mol Med 12:1072-1073, 2008. [Abstract]

Towner RA, Smith N, Doblas S, Tesiram Y, Garteiser P, Saunders D, Cranford R, Silasi-Mansat R, Herlea O, Ivanciu L, Wu D, Lupu F. In vivo detection of c-Met expression in a rat C6 glioma model. J Cell Mol Med 12:174-186, 2008. [Abstract]

Selected Publications
Zhu H, Tang Y, Ivanciu L, Centola M, Lupu C, Taylor FB, Jr., Lupu F. Temporal dynamics of gene expression in the lung in a baboon model of E. coli sepsis. BMC Genomics 8:58, 2007. [Abstract]

Collen A, Hanemaaijer R, Lupu F, Quax PH, Van Lent N, Grimbergen J, Peters E, Koolwijk P, Van Hinsbergh VW. Membrane-type matrix metalloproteinase mediated angiogenesis in a fibrin-collagen matrix. Blood 101:1810-1817, 2003. [Abstract]

Compernolle V, Brusselmans K, Acker T, Hoet P, Tjwa M, Beck H, Plaisance S, Dor Y, Keshet E, Lupu F, Nemery B, Dewerchin M, Van Veldhoven P, Plate K, Moons L, Collen D, Carmeliet P. Loss of HIF-2 alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fetal respiratory distress in premature mice. Nat Med 8:702-710, 2002. [Abstract] Erratum in: Nat Med 8:1320, 2002.

Conway EM, Pollefeyt S, Steiner-Mosonyi M, Luo W, Devriese A, Lupu F, Bono F, Leducq N, Dol F, Schaeffer P, Collen D, Herbert JM. Deficiency of survivin in transgenic mice exacerbates Fas-induced apoptosis via mitochondrial pathways. Gastroenterology 123:619-631, 2002. [Abstract]

Crawley JT, Goulding DA, Ferreira V, Severs NJ, Lupu F. Expression and localization of tissue factor pathway inhibitor-2 in normal and atherosclerotic human vessels. Arterioscler Thromb Vasc Biol 22:218-224, 2002. [Abstract]

Luttun A, Lupu F, Storkebaum E, Hoylaerts MF, Moon L, Crawley J, Bono F, Poole AR, Tipping P, Herbert JM, Collen D, Carmeliet P. Lack of plasminogen activator inhibitor-1 promotes growth and abnormal matrix remodeling of advanced atherosclerotic plaques in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol 22:499-505, 2002. [Abstract]