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Publications

Cardiovascular Biology Research Program

Fletcher B. Taylor, M.D. Member, Cardiovascular Biology Research Program Adjunct Professor, Departments of Pathology, Biochemistry & Molecular Biology   and Physiology & Biophysics George Lynn Cross Research Professor, University of Oklahoma Health Sciences   Center OMRF Distinguished Career Scientist

Recent Publications
Xu J, Zhang X, Pelayo R, Monestier M, Ammollo CT, Semeraro F, Taylor FB, Esmon NL, Lupu F, Esmon CT.  Extracellular histones are major mediators of death in sepsis.  Nat Med 15:1318-1321, 2009.  [Abstract]

Binette TM, Taylor FB Jr, Peer G, Bajzar L.  Thrombin-thrombomodulin connects coagulation and fibrinolysis: more than an in vitro phenomenon.  Blood 110:3168-3175, 2007.  [Abstract]

Samis JA, Stewart KA, Nesheim ME, Taylor FB Jr.  Factor V cleavage and inactivation are temporally associated with elevated elastase during experimental sepsis.  J Thromb Haemost 5:2559-2561, 2007.  [Abstract]

Selected Publications
Samis JA, Stewart KA, Nesheim ME, Taylor FB Jr. Time-dependent association between coagulation factor inactivation and increased elastase during experimental sepsis. J Thromb Haemost 7:1032-1034, 2009. [Abstract]

Mehta A, Brewington R, Chatterji M, Zoubine M, Kinasewitz GT, Peer GT, Chang ACK, Taylor FB and Shnyra A. Infection-induced modulation of M1 and M2 phenotypes in circulating monocytes: Role in immune monitoring and early prognosis of sepsis. Shock 22:423-430, 2004. [Abstract]

Taylor FB and Kinasewitz G. Activated protein C in sepsis. J Thromb Haemost 2:708-717, 2004. [Abstract]

Siegler RL, Obrig TG, Pysher TJ, Tesh VL, Denkers ND and Taylor FB. Response to Shiga toxin 1 and 2 in a baboon model of hemolytic uremic syndrome. Pediatr Nephrol 18:92-96, 2003. [Abstract]

Taylor F, Jr. comment of "Drotrecogin Alfa (activated) (recombinant human protein C, rhAPC) reduces host coagulopathy response in patients with severe sepsis." Thromb Haemost 90:560-561, 2003. [Abstract]

Pysher TJ, Siegler RL, Tech VL, Taylor FB Jr. von Willebrand factor expression in a Shiga toxin-mediated primate model of hemolytic uremic syndrome. Pediatr Dev Pathol 5:472-479, 2002. [Abstract]