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Arthritis and Immunology Research Program

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OMRF receives $26 million for two federal research grants

Jonathan D. Wren, Ph.D. Assistant Member, Arthritis and Immunology Research Program

Recent Publications
Wren JD. A global meta-analysis of microarray expression data to predict unknown gene functions and estimate the literature-data divide. Bioinformatics 25:1694-1701, 2009. [Abstract]

Webb R, Wren JD, Jeffries M, Kelly JA, Kaufman KM, Tang Y, Frank MB, Merrill J, Kimberly RP, Edberg JC, Ramsey-Goldman R, Petri M, Reveille JD, Alarcon GS, Vila LM, Alarcón-Riquelme ME, James JA, Vyse TJ, Moser KL, Gaffney PM, Gilkeson GS, Harley JB, Sawalha AH. Variants within MECP2, a key transcription regulator, are associated with increased susceptibility to lupus and differential gene expression in patients with systemic lupus erythematosus. Arthritis Rheum 60:1076-1084, 2009. [Abstract]

Wren JD, Wilkins D, Fuscoe JC, Bridges S, Winters-Hilt S, Gusev Y. Proceedings of the 2008 MidSouth Computational Biology and Bioinformatics Society (MCBIOS) Conference. BMC Bioinformatics 9 Suppl 9:S1, 2008. [Abstract]

Selected Publications
Wren JD, Wu Y, Guo SW. A system-wide analysis of differentially expressed genes in ectopic and eutopic endometrium. Hum Reprod 22:2093-2102, 2007. [Abstract]

Wren JD. A scalable machine-learning approach to recognize chemical names within large text databases. BMC Bioinformatics 7 Suppl 2:S3, 2006. [Abstract]

Wren JD, Roossinck MJ, Nelson RS, Scheets K, Palmer MW, Melcher U. Plant virus biodiversity and ecology. PLoS Biol 4:e80, 2006. [Abstract]

Wren JD. Open access and openly accessible: a study of scientific publications shared via the internet. BMJ 330:1128, 2005. [Abstract]

Wren JD, Hildebrand WH, Chandrasekaran S, Melcher U. Markov model recognition and classification of DNA/protein sequences within large text databases. Bioinformatics 21:4046-4053, 2005. [Abstract]

Wren JD, Bekeredjian R, Stewart JA, Shohet RV, Garner HR. Knowledge discovery by automated identification and ranking of implicit relationships. Bioinformatics 20:389-398, 2004. [Abstract]