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Dr. Farris:

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Dr. Farris' CV in brief

Publications

Arthritis and Immunology Research Program

Dr. Farris In The News

OMRF anthrax discovery could lead to improved vaccine

Hiding in Plain Sight: OMRF researchers discover rogue immune cells in healthy adults

A. Darise Farris, Ph.D. Associate Member, Arthritis and Immunology Research Program Adjunct Associate Professor, Departments of Microbiology & Immunology and   Pathology, University of Oklahoma Health Sciences Center

Research Interests
The primary focus of our laboratory is to understand tolerance and autoimmunity to ubiquitous nuclear antigens that are targeted in systemic autoimmune diseases such as systemic lupus erythematosus and Sjögren’s syndrome. Using a human La (SS-B) transgenic mouse model and novel T cell receptor and B cell receptor transgenic models, we are delineating mechanisms of T and B cell tolerance to this ubiquitous, RNA-binding nuclear antigen.

A second major effort in our laboratory is to use animal models to decipher details of the neutralizing antibody response to major antigenic targets of Bacillus anthracis and then to use this information to improve current vaccine strategies to this bioterror threat.

Joined OMRF Scientific Staff in 1999.

Mailing Address
Arthritis and Immunology Research Program, MS 24
Oklahoma Medical Research Foundation
825 N.E. 13th Street
Oklahoma City, Oklahoma 73104

Contact Information
Phone: (405) 271-7389
Fax: (405) 271-4110
E-mail: Darise-Farris@omrf.org