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More about Dr. Rankin 101 Cell Cycle and Cancer Biology Research Program Dr. Rankin In The News OMRF cell biologist honored as Oklahoma's first Pew Scholar
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Dr. Rankin studies the manner in which cells control the key events of cell division. When cells divide, either in order to develop new tissues or to replace aging or defective cells, a precise and highly complex series of cellular events must be carefully coordinated. This coordination ensures that newly forming cells inherit the appropriate components and thus are able to function properly. In the course of experiments developed to better understand the control of cell division, Dr. Rankin has identified a novel gene that is necessary to ensure accurate chromosome segregation to newly forming cells. Because the chromosomes carry essentially all genetic information within a cell, their accurate segregation during cell division is critical. In addition, errors in chromosome segregation are known to play an important role in the development of tumors, making a better understanding of this process a very worthy endeavor. Dr. Rankin uses several approaches to understand further the regulation of chromosome segregation. These include biochemical analyses using extracts from eggs of the frog Xenopus laevis and time-lapse image analysis of cultured cells.
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