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Research | Core Facilities | Patient Studies | Tech Transfer | Seminars | Intranet | Jobs | Search | Contact Us | Ways To Give HOME |
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Publications
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OMRF Publications For 2004 Arthritis Research Program Dozmorov,I., N.Knowlton, Y.Tang, and M.Centola. 2004. Statistical monitoring of weak spots for improvement of normalization and ratio estimates in microarrays. BMC.Bioinformatics 5:53. [Abstract] Dozmorov,I., N.Knowlton, Y.Tang, A.Shields, P.Pathipvanich, J.N.Jarvis, and M.Centola. 2004. Hypervariable genes--experimental error or hidden dynamics. Nucleic Acids Res 32:e147. [Abstract] Gomez,M., R.M.Clark, S.K.Nath, S.Bhatti, R.Sharma, E.Alonso, A.Rasmussen, and S.I.Bidichandani. 2004. Genetic admixture of European FRDA genes is the cause of Friedreich ataxia in the Mexican population. Genomics 84:779-784. [Abstract] Hitchon,C.A., P.Alex, L.B.Erdile, M.B.Frank, I.Dozmorov, Y.Tang, K.Wong, M.Centola, and H.S.El Gabalawy. 2004. A distinct multicytokine profile is associated with anti-cyclical citrullinated Peptide antibodies in patients with early untreated inflammatory arthritis. J Rheumatol. 31:2336-2346. [Abstract] James JA, Aggarwal AK,
Linden RM, Escalante CR. Structure of adeno-associated virus type 2
Rep40-ADP complex: insight into nucleotide recognition and catalysis by
superfamily 3 helicases. Proc Natl Acad Sci U S A 101:12455-12460,
2004.
[Abstract] Jarvis,J.N., I.Dozmorov, K.Jiang, M.B.Frank, P.Szodoray, P.Alex, and M.Centola. 2004. Novel approaches to gene expression analysis of active polyarticular juvenile rheumatoid arthritis. Arthritis Res.Ther. 6:R15-R32. [Abstract] Jorgensen,E.D., I.Dozmorov, M.B.Frank, M.Centola, and A.P.Albino. 2004. Global Gene Expression Analysis of Human Bronchial Epithelial Cells Treated with Tobacco Condensates. Cell Cycle 3:1154-1168. [Abstract] Knowlton,N., I.M.Dozmorov, and M.Centola. 2004. Microarray data analysis toolbox (MDAT): for normalization, adjustment and analysis of gene expression data. Bioinformatics. 20: 3687-3690. [Abstract] * Kolar,G.R., T.Yokota, M.I.Rossi, S.K.Nath, and J.D.Capra. 2004. Human fetal, cord blood, and adult lymphocyte progenitors have similar potential for generating B cells with a diverse immunoglobulin repertoire. Blood. 104:2981-7. [Abstract] Kurien,B.T., N.E.Everds, and R.H.Scofield. 2004. Experimental animal urine collection: a review. Lab Anim 38:333-361. [Abstract] Kurien,B.T., N.C.Patel, A.C.Porter, S.Kurono, H.Matsumoto, H.Wang, and R.H. Scofield. 2004. Determination of prolidase activity using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Anal.Biochem. 331:224-229. [Abstract] * Kurien,B.T., B.W.Pillow, Y.Dorri, K.Hensley, M.Bachman, and R.H.Scofield. 2004. SOD1 interacts directly with hemoglobin in vitro. Thromb.Haemost. 92:218-220. [Abstract] Kurien,B.T., A.C.Porter, N.C.Patel, S.Kurono, H.Matsumoto, and R.H.Scofield. 2004. Mechanized syringe homogenization of human and animal tissues. Assay.Drug Dev.Technol. 2:308-312. [Abstract] McClain,M.T., M.R.Arbuckle, L.D.Heinlen, G.J.Dennis, J.Roebuck, M.V.Rubertone, J.B.Harley, and J.A.James. 2004. The prevalence, onset, and clinical significance of antiphospholipid antibodies prior to diagnosis of systemic lupus erythematosus. Arthritis Rheum. 50:1226-1232. [Abstract] McClain,M.T., C.S.Lutz, K.M.Kaufman, O.Z.Faig, T.F.Gross, and J.A.James. 2004. Structural availability influences the capacity of autoantigenic epitopes to induce a widespread lupus-like autoimmune response. Proc.Natl.Acad.Sci.U.S.A. 101:3551-3556. [Abstract] Nath,S.K., J.A.Kelly, J.B.Harley, and R.H.Scofield. 2004. Mapping the systematic lupus erythematosus susceptibility genes. Methods Mol Med. 102:11-30. [Abstract] Nath,S.K., J.Kilpatrick, and J.B.Harley. 2004. Genetics of human systemic lupus erythematosus: the emerging picture. Curr Opin.Immunol. 16:794-800. [Abstract] Nath,S.K., B.Namjou, C.P.Garriott, S.Frank, P.A.Joslin, J.Kilpatrick, J.A.Kelly, and J.B.Harley. 2004. Linkage analysis of SLE susceptibility: confirmation of SLER1 at 5p15.3. Genes Immun. 5:209-214. [Abstract] Nath,S.K., B.Namjou, D.Hutchings, C.P.Garriott, C.Pongratz, J.Guthridge, and J.A.James. 2004. Systemic lupus erythematosus (SLE) and chromosome 16: confirmation of linkage to 16q12-13 and evidence for genetic heterogeneity. Eur.J.Hum.Genet. 12:668-72. [Abstract] Nath,S.K., B.Namjou, J.Kilpatrick, C.P.Garriott, G.R.Bruner, R.H.Scofield, and J.B.Harley. 2004. A candidate region on 11p13 for systemic lupus erythematosus: A linkage identified in African-American families. J Invest Dermatol Symp Proc 9:64-67. [Abstract] Nath,S.K., A.I.Quintero-Del-Rio, J.Kilpatrick, L.Feo, M.Ballesteros, and J.B.Harley. 2004. Linkage at 12q24 with Systemic Lupus Erythematosus (SLE) Is Established and Confirmed in Hispanic and European American Families. Am.J.Hum.Genet. 74:73-82. [Abstract] Nunlist,E.H., I.Dozmorov, Y.Tang, R.Cowan, M.Centola, and H.K.Lin. 2004. Partitioning of 5alpha-dihydrotestosterone and 5alpha-androstane-3alpha, 17beta-diol activated pathways for stimulating human prostate cancer LNCaP cell proliferation. J Steroid Biochem.Mol Biol 91:157-170. [Abstract] O'Hanlon,T., B.Koneru, E.Bayat, L.Love, I.Targoff, J.Malley, K.Malley, and F.Miller. 2004. Immunogenetic differences between Caucasian women with and those without silicone implants in whom myositis develops. Arthritis Rheum 50:3646-3650. [Abstract] Quintero-del-Rio,A.I., J.A.Kelly, C.P.Garriott, D.C.Hutchings, S.G.Frank, C.E.Aston, and J.B.Harley. 2004. SLEN2 (2q34-35) and SLEN1 (10q22.3) replication in systemic lupus erythematosus stratified by nephritis. Am.J Hum.Genet. 75:346-348. Sawalha,A.H. and J.B.Harley. 2004. Antinuclear autoantibodies in systemic lupus erythematosus. Curr Opin.Rheumatol. 16:534-540. [Abstract] Sawalha,A.H., W.R.Schmid, S.R.Binder, D.K.Bacino, and J.B.Harley. 2004. Association between systemic lupus erythematosus and Helicobacter pylori seronegativity. J Rheumatol. 31:1546-1550. [Abstract] Scofield,R.H. 2004. Autoantibodies as predictors of disease. Lancet 363:1544-1546. [Abstract] Scofield,R.H. 2004. Genetic knock out of 60kD Ro (or SSA), a common lupus autoantigen, induces lupus. Trends Immunol. 25:1-3. [Abstract] Scofield,R.H., B.T.Kurien, J.K.Gross, N.B.Reed, A.K.Taylor, N.Dominguez, P.Mehta, J.M.Guthridge, and M.Bachmann. 2004. Interaction of calcium and Ro60: increase of antigenicity. Mol Immunol. 41:809-816. [Abstract] Shenoi,J., B.T.Kurien, S.Kurono, R.Mascarenhas, H.Matsumoto, and R.H.Scofield. 2004. Cost-benefit analysis of a method using diatomaceous earth to purify Tamm-Horsfall protein. Biotechniques 36:64-66. [Abstract] Szodoray,P., P.Alex, J.G.Brun, M.Centola, and R.Jonsson. 2004. Circulating cytokines in primary Sjogren's syndrome determined by a multiplex cytokine array system. Scand.J Immunol. 59:592-599. [Abstract] Szodoray,P., P.Alex, V.Dandapani, B.Nakken, J.Pesina, X.Kim, G.L.Wallis, P.C.Wilson, R.Jonsson, and M.Centola. 2004. Apoptotic effect of rituximab on peripheral blood B cells in rheumatoid arthritis. Scand.J.Immunol. 60:209-218. [Abstract] * Szodoray P., S. Jellestad, P. Alex, T. Zhou, P.C. Wilson, M.Centola,J.B. Brun, R.Jonsson. 2004. Programmed cell death of peripheral blood B cells determined by laser scanning cytometry in Sjogren's syndrome with a special emphasis on BAFF. J Clin Immunol 24:600-611, 2004. [Abstract] Zimmerman,R.A., I.Dozmorov, E.H.Nunlist, Y.Tang, X.Li, R.Cowan, M.Centola, M.B.Frank, D.J.Culkin, and H.K.Lin. 2004. 5alpha-Androstane-3alpha,17beta-diol activates pathway that resembles the epidermal growth factor responsive pathways in stimulating human prostate cancer LNCaP cell proliferation. Prostate Cancer Prostatic.Dis. 7:364-374. [Abstract] Cardiovascular Biology Research Program Annamalai,R., B.Jin, Z.H.Cao, S.M.C.Newton, and P.E.Klebba. 2004. Recognition of ferric catecholates by FepA. J Bacteriol 186:3578-3589. [Abstract] Dhainaut,J.F., W.Aird, and C.Esmon. 2004. Introduction to the Fifth Margaux Conference on Critical Illness: Protein C pathways: Bedside to bench. Crit Care Med. 32:S193. [Abstract] Esmon,C.T. 2004. Crosstalk between inflammation and thrombosis. Maturitas 47:305-314. [Abstract] Esmon,C.T. 2004. The impact of the inflammatory response on coagulation. Thromb Res 114:321-327. [Abstract] Esmon,C.T. 2004. Interactions between the innate immune and blood coagulation systems. Trends Immunol. 25:536-542. [Abstract] Esmon,C.T. 2004. Structure and functions of the endothelial cell protein C receptor. Crit Care Med. 32:S298-S301. [Abstract] Esmon,C.T. 2004. Why do animal models (sometimes) fail to mimic human sepsis? Crit Care Med. 32:S219-S222. [Abstract] Esmon,C.T. and W.G.Owen. 2004. The discovery of thrombomodulin. J.Thromb.Haemost. 2:209-213. {Abstract] * Huang,X.P., W.P.Chang, G.Koelsch, R.Turner, III, F.Lupu, and J.Tang. 2004. Internalization of exogenously added memapsin 2 (beta -secretase) ectodomain by cells Is mediated by amyloid precursor protein. J Biol Chem. 279:37886-37894 [Abstract] Huang,J., J.Chen, S.E.Chesla, T.Yago, P.Mehta, R.P.Mcever, C.Zhu, and M.Long. 2004. Quantifying the effects of molecular orientation and length on two-dimensional receptor-ligand binding kinetics. J Biol Chem 279:44915-44923. [Abstract] Jin,X., A.P.Malykhina, F.Lupu, and H.I.Akbarali. 2004. Altered gene expression and increased bursting activity of colonic smooth muscle ATP-sensitive K+ channels in experimental colitis. Am.J.Physiol Gastrointest.Liver Physiol. 287:G274-G285. [Abstract] Kappelmayer,J., B.Nagy,
K.Miszti-Blasius, Z.Hevessy, and H.Setiadi. 2004. The emerging value of P-selectin
as a disease marker. Clin Chem Lab Med 42:475-486. Kinasewitz,G.T., S.B.Yan, B.Basson, P.Comp, J.A.Russell, A.Cariou, S.L.Um, B.Utterback, P.F.Laterre, and J.F.Dhainaut. 2004. Universal changes in biomarkers of coagulation and inflammation occur in patients with severe sepsis, regardless of causative micro-organism [ISRCTN74215569]. Crit Care 8:R82-R90. [Abstract] Li,W., D.J.Johnson, C.T.Esmon, and J.A.Huntington. 2004. Structure of the antithrombin-thrombin-heparin ternary complex reveals the antithrombotic mechanism of heparin. Nat.Struct Mol Biol 11:857-862. [Abstract] Liaw,P.C., C.T.Esmon, K.Kahnamoui, S.Schmidt, S.Kahnamoui, G.Ferrell, S.Beaudin, J.A.Julian, J.I.Weitz, M.Crowther, M.Loeb, and D.J.Cook. 2004. Patients with severe sepsis vary markedly in their ability to generate activate protein C. Blood. 104:3958-3964. [Abstract] Marcus, W.D., McEver, R.P., and C. Zhu. Forces required to initiate membrane tether extrusion from cell surface depend on cell type but not on the surface molecule. Mech Chem Biosyst 1:245-251, 2004. [Abstract] Mehta,A., R.Brewington, M.Chatterji, M.Zoubine, G.T.Kinasewitz, G.T.Peer, A.C.K.Chang, F.B.Taylor, and A.Shnyra. 2004. Infection-induced modulation of M1 and M2 phenotypes in circulating monocytes: Role in immune monitoring and early prognosis of sepsis. Shock 22:423-430. [Abstract] Ramachandran,V., M.Williams, T.Yago, D.W.Schmidtke, and R.P.Mcever. 2004. Dynamic alterations of membrane tethers stabilize leukocyte rolling on P-selectin. Proc Natl Acad Sci U S A 101:13519-13524. [Abstract] Rijneveld,A.W., S.Weijer, S.Florquin, C.T.Esmon, J.C.Meijers, P.Speelman, P.H.Reitsma, H.ten Cate, and P.T.Van Der. 2004. Thrombomodulin mutant mice with a strongly reduced capacity to generate Activated Protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide. Blood.103:1702-9. [Abstract] Sarangapani,K.K., T.Yago, A.G.Klopocki, M.B.Lawrence, C.B.Fieger, S.D.Rosen, R.P.McEver, and C.Zhu. 2004. Low force decelerates L-selectin dissociation from P-selectin glycoprotein ligand-1 and endoglycan. J Biol Chem 279:2291-2298. [Abstract] Svensson,A.M., B.L.Waters, Z.G.Laszik, L.Simmons-Arnold, A.Goodwin, B.G.Beatty, and E.G.Bovill. 2004. The protein C system in placental massive perivillous fibrin deposition. Blood Coagul Fibrinolysis 15:491-495. [Abstract] Szodoray,P., P.Alex, V.Dandapani, B.Nakken, J.Pesina, X.Kim, G.L.Wallis, P.C.Wilson, R.Jonsson, and M.Centola. 2004. Apoptotic effect of rituximab on peripheral blood B cells in rheumatoid arthritis. Scand.J Immunol. 60:209-218. [Abstract] Taylor,F.B. and G.Kinasewitz. 2004. Activated protein C in sepsis. J.Thromb.Haemost. 2:708-717 [Abstract] Xia,L., T.Ju, A.Westmuckett, G.An, L.Ivanciu, J.M.McDaniel, F.Lupu, R.D.Cummings, and R.P.McEver. 2004. Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans. J.Cell Biol. 164:451-459. [Abstract] Xia,L., J.M.McDaniel, T.Yago, A.Doeden, and R.P.McEver. 2004. Surface fucosylation of human cord blood cells augments binding to P-selectin and E-selectin and enhances engraftment in bone marrow. Blood. 104:3091-3096. [Abstract] Yago,T., J.Wu, C.D.Wey, A.G.Klopocki, C.Zhu, and R.P.McEver. 2004. Catch bonds govern adhesion through L-selectin at threshold shear. J Cell Biol 166:913-923. [Abstract] Zhuang,D., A.C.Ceacareanu, Y.Lin, B.Ceacareanu, M.Dixit, K.E.Chapman, C.M.Waters, G.N.Rao, and A.Hassid. 2004. Nitric oxide attenuates insulin- or IGF-I-stimulated aortic smooth muscle cell motility by decreasing H2O2 levels: essential role of cGMP. Am.J Physiol Heart Circ.Physiol 286:H2103-H2112. [Abstract] Clinical Pharmacology Research Program Horita,T. and J.T.Merrill. 2004. Genetics of antiphospholipid syndrome. Curr Rheumatol.Rep. 6:458-462. [Abstract] Lopez,L.R., K.J.Dier, D.Lopez, J.T.Merrill, and C.A.Fink. 2004. Anti-beta 2-glycoprotein I and antiphosphatidylserine antibodies are predictors of arterial thrombosis in patients with antiphospholipid syndrome. Am.J.Clin.Pathol. 121:142-149. [Abstract] Merrill,J.T. 2004. Antibodies and clinical features of the antiphospholipid syndrome as criteria for systemic lupus erythematosus. Lupus 13:869-876. [Abstract] Merrill,J.T. 2004. Diagnosis of the antiphospholipid syndrome: how far to go? Curr Rheumatol.Rep. 6:469-472. [Abstract] Merrill,J.T. 2004. LJP 1082: a toleragen for Hughes syndrome. Lupus 13:335-338. [Abstract] Merrill,J.T., D.Erkan, and J.P.Buyon. 2004. Challenges in bringing the bench to bedside in drug development for sle. Nat.Rev.Drug Discov. 3:1036-1046. [Abstract] Petri,M.A., P.J.Mease, J.T.Merrill, R.G.Lahita, M.J.Iannini, D.E.Yocum, E.M.Ginzler, R.S.Katz, O.S.Gluck, M.C.Genovese, R.Van Vollenhoven, K.C.Kalunian, S.Manzi, M.W.Greenwald, J.P.Buyon, N.J.Olsen, M.H.Schiff, A.F.Kavanaugh, J.R.Caldwell, R.Ramsey-Goldman, E.W.St Clair, A.L.Goldman, R.M.Egan, R.P.Polisson, K.G.Moder, N.F.Rothfield, R.T.Spencer, K.Hobbs, B.J.Fessler, L.H.Calabrese, L.W.Moreland, S.B.Cohen, B.J.Quarles, V.Strand, M.Gurwith, and K.E.Schwartz. 2004. Effects of prasterone on disease activity and symptoms in women with active systemic lupus erythematosus. Arthritis Rheum 50:2858-2868. [Abstract] Wollaston,S.J., V.T.Farewell, D.A.Isenberg, C.Gordon, J.T.Merrill, M.A.Petri, and K.C.Kalunian. 2004. Defining response in systemic lupus erythematosus: a study by the Systemic Lupus International Collaborating Clinics group. J Rheumatol. 31:2390-2394. [Abstract] Comparative Medicine/LARC * Booth,J.L., K.M.Coggeshall, B.E.Gordon, and J.P.Metcalf. 2004. Adenovirus Type 7 Induces Interleukin-8 in a Lung Slice Model and Requires Activation of Erk. J.Virol. 78:4156-4164. [Abstract] * Chang,W.P., G.Koelsch, S.Wong, D.Downs, H.Da, V.Weerasena, B.Gordon, T.Devasamudram, G.Bilcer, A.K.Ghosh, and J.Tang. 2004. In vivo inhibition of Abeta production by memapsin 2 (beta-secretase) inhibitors. J Neurochem. 89416. [Abstract] Crystallography Research Program Bourne,P.C., S.S.Terzyan, G.Cloud, N.F.Landolfi, M.Vasquez, and A.B.Edmundson. 2004. Three-dimensional structures of a humanized anti-IFN-gamma Fab (HuZAF) in two crystal forms. Acta Crystallogr.D Biol Crystallogr. 60:1761-1769. [Abstract] Li,G.P. and X.J.C.Zhang. 2004. GTP hydrolysis mechanism of Ras-like GTPases. J Mol Biol 340:921-932. [Abstract] Paul,S., S.Karle, S.Planque, H.Taguchi, M.Salas, Y.Nishiyama, B.Handy, R.Hunter, A.Edmundson, and C.Hanson. 2004. Naturally occurring proteolytic antibodies: Selective IgM-catalyzed hydrolysis of HIV gp120. J Biol Chem. 279: 39611-39619 [Abstract] Planque,S., Y.Bangale, X.T.Song, S.Karle, H.Taguchi, B.Poindexter, R.Bick, A.Edmundson, Y.Nishiyama, and S.Paul. 2004. Ontogeny of proteolytic immunity - IgM serine proteases. J Biol Chem 279:14024-14032. [Abstract] Terzyan,S., G.Zhu, G.Li, and X.C.Zhang. 2004. Refinement of the structure of human Rab5a GTPase domain at 1.05 A resolution. Acta Crystallogr.D.Biol.Crystallogr. 60:54-60. [Abstract] Terzyan,S.S., H.A.Karapetyan, R.B.Sukiasyan, and A.M.Petrosyan. 2004. L-arginine nitrates. J Mol Struct 687:111-117. Terzyan,S., P.A.Ramsland, E.W.Voss, Jr., J.N.Herron, and A.B.Edmundson. 2004. Three-dimensional structures of idiotypically related Fabs with intermediate and high affinity for fluorescein. J Mol Biol 339:1141-1151. [Abstract] Terzyan,S., N.Wakeham, P.Zhai, K.Rodgers, and X.J.C.Zhang. 2004. Characterization of Lys-698 to Met substitution in human plasminogen catalytic domain. Proteins 56:277-284. [Abstract] Zhang,Z., S.M.Lapolla, M.G.Annis, M.Truscott, G.J.Roberts, Y.W.Miao, Y.L.Shao, C.B.Tan, J.Peng, A.E.Johnson, X.J.C.Zhang, D.W.Andrews, and J.L.Lin. 2004. Bcl-2 homodimerization involves two distinct binding surfaces, a topographic arrangement that provides an effective mechanism for Bcl-2 to capture activated Bax. J Biol Chem 279:43920-43928. [Abstract] * Zhu,G., P.Zhai, X.He, N.Wakeham, K.Rodgers, G.Li, J.Tang, and X.C.Zhang. 2004. Crystal structure of human GGA1 GAT domain complexed with the GAT-binding domain of Rabaptin5. EMBO J 23:3909-3917. {Abstract] Zhu,G.Y., P.Zhai, J.Liu, S.Terzyan, G.P.Li, and X.J.C.Zhang. 2004. Structural basis of Rab5-Rabaptin5 interaction in endocytosis. Nat Struct Mol Biol 11:975-983. [Abstract] Free Radical Biology and Aging Research Program Floyd,R.A., J.E.Schneider, Jr., and D.P.Dittmer. 2004. Methylene blue photoinactivation of RNA viruses. Antiviral Res. 61:141-151. [Abstract] Grammas,P., L.Hamdheydari, E.J.Benaksas, S.Mou, Q.N.Pye, W.J.Wechter, R.A.Floyd, C.Stewart, and K.Hensley. 2004. Anti-inflammatory effects of tocopherol metabolites. Biochem.Biophys.Res.Commun. 319:1047-1052. [Abstract] Guo,W.X., Q.N.Pye, K.S.Williamson, C.A.Stewart, K.L.Hensley, Y.Kotake, R.A.Floyd, and R.H.Broyles. 2004. Reactive oxygen species in choline deficiency-induced apoptosis in rat hepatocytes. Free Radic.Biol Med. 37:1081-1089. [Abstract] Hensley,K., E.J.Benaksas, R.Bolli, P.Comp, P.Grammas, L.Hamdheydari, S.Mou, Q.N.Pye, M.F.Stoddard, G.Wallis, K.S.Williamson, M.West, W.J.Wechter, and R.A.Floyd. 2004. New perspectives on vitamin E: gamma-tocopherol and carboxyethylhydroxychroman metabolites in biology and medicine Free Radic.Biol.Med. 36:1-15. [Abstract] Kim,Y.T., R.Kurita, M.Kojima, W.Nishii, M.Tanokura, T.Muramatsu, H.Ito, and K.Takahashi. 2004. Identification of arginine residues important for the activity of Escherichia coli signal peptidase I. Biol Chem 385:381-388. [Abstract] * Kurien,B.T., B.W.Pillow, Y.Dorri, K.Hensley, M.Bachman, and R.H.Scofield. 2004. SOD1 interacts directly with hemoglobin in vitro. Thromb.Haemost. 92:218-220. [Abstract] Maples,K.R., A.R.Green, and R.A.Floyd. 2004. Nitrone-Related Therapeutics : Potential of NXY-059 for the Treatment of Acute Ischaemic Stroke. CNS.Drugs 18:1071-1084. [Abstract] Mhatre,M., R.A.Floyd, and K.Hensley. 2004. Oxidative stress and neuroinflammation in Alzheimer's disease and amyotrophic lateral sclerosis: Common links and potential therapeutic targets. J.Alzheimers.Dis. 6:147-157. [Abstract] Mhatre,M., A.Nguyen, S.Kashani, T.Pham, A.Adesina, and P.Grammas. 2004. Thrombin, a mediator of neurotoxicity and memory impairment. Neurobiol.Aging 25:783-793. [Abstract] Mhatre,M., R.Pruthi, K.Hensley, and F.Holloway. 2004. 5-HT(3) antagonist ICS 205-930 enhances naltrexone's effects on ethanol intake. Eur.J.Pharmacol. 491:149-156. [Abstract] Nakae,D., F.Uematsu, H.Kishida, O.Kusuoka, S.Katsuda, M.Yoshida, M.Takahashi, A.Maekawa, A.Denda, Y.Konishi, Y.Kotake, and R.A.Floyd. 2004. Inhibition of the development of hepatocellular carcinomas by phenyl N-tert-butyl nitrone in rats fed with a choline-deficient, l-amino acid-defined diet. Cancer Lett. 206:1-13. [Abstract] Sueishi,Y., H.Tobisako, and Y.Kotake. 2004. Distinctive pressure effects on the association equilibrium in cyclodextrin group-inclusion complex as studied with electron paramagnetic resonance. J Phys Chem B 108:12623-12627. Towner,R.A., C.Appleby, M.Levy, and T.M.Bray. 2004. Zinc deficiency and oxidative stress in brain: Magnetic resonance investigations in weanling rats. J Trace Elem Exp Med 17:161-174. West,M., M.Mhatre, A.Ceballos, R.A.Floyd, P.Grammas, S.P.Gabbita, L.Hamdheydari, T.Mai, S.Mou, Q.N.Pye, C.Stewart, S.West, K.S.Williamson, F.Zemlan, and K.Hensley. 2004. The arachidonic acid 5-lipoxygenase inhibitor nordihydroguaiaretic acid inhibits tumor necrosis factor alpha activation of microglia and extends survival of G93A-SOD1 transgenic mice. J Neurochem. 91:133-143. [Abstract] Yoshimura,T. and Y.Kotake. 2004. Spin trapping of nitric oxide with the iron-dithiocarbamate complex: chemistry and biology. Antioxid.Redox.Signal. 6:639-647. [Abstract] Yoshioka,C., Y.Kotake, and Y.Sueishi. 2004. External pressure modulates spin-trapping rates in solution as studied with electron spin resonance. Chem Phys Lett 385:189-192. Immunobiology and Cancer Research Program Baba,Y., R.Pelayo, and P.W.Kincade. 2004. Relationships between hematopoietic stem cells and lymphocyte progenitors. Trends Immunol. 25:645-649. [Abstract] * Booth,J.L., K.M.Coggeshall, B.E.Gordon, and J.P.Metcalf. 2004. Adenovirus Type 7 Induces Interleukin-8 in a Lung Slice Model and Requires Activation of Erk. J.Virol. 78:4156-4164. [Abstract] Eltzschig HK, L.F.Thompson, J. 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