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Microarray Research Facility

Introduction

Personnel/Contact Us

Experimental Design

RNA Needed

RNA Quality

Frequently Asked Questions

Bioinformatics

Equipment

Protocols

Publications

Oklahoma Microarray INBRE Labs

Other Core Facilities

 

 

Introduction
Microarrays allow the simultaneous measurement of expression levels of thousands of genes in cells or tissues under different physiological or disease states. Scientists at the OMRF Microarray Research Facility collaborate with researchers here and around the world to study differential gene expression in order to understand pathophysiologic states at the molecular levels.

Microarray Core Services
Users are encouraged to contact the OMRF Microarray Research Facility to discuss details of experimental design prior to isolating RNA for microarray experiments. RNA should be prepared by each investigator and delivered to the Facility. RNA quantity and quality will be assessed by our staff. Only samples with good quality RNA will advance to labeling, hybridization, data collection and analysis phases.

The OMRF Microarray Research Facility currently offers two commercial micorarray platforms for genome wide expression studies:

  • Affymetrix GeneChip® microarrays

  • Illumina Sentrix® Expression BeadChip microarrays

  • Affymetrix microarrays are available for gene expression studies for a large number of species. (Click here to review Affymetrix products.) Illumina gene expression arrays offer a high quality, cost effective alternative to investigators for studying gene expression in humans and mouse or rat models. (Click here to review Illumina products.) Protein arrays are currently under evaluation by our staff.

    Contact Us
    Researchers may contact us by e-mail or phone (405-271-8468) to discuss the application of microarrays to your research.
    Bart Frank, PhD
    Mike Centola, PhD
    Craig Cadwell, PhD
    Jeanie Osban
    Nick Knowlton